Health & Care INNOVATION
A set of clinically driven multiscale hypermodels simulating tumor growth and response to treatment
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Market Maturity: Tech Ready
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Market Creation Potential
This innovation was assessed by the JRC’s Market Creation Potential indicator framework as having a Very high” level of Market Creation Potential. Only innovations that are showing multiple signals of market creation potential are assigned a value under this indicator system. Learn more
Go to Market needs
Needs that, if addressed, can increase the chances this innovation gets to (or closer to) the market incude:
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Location of Key Innovators developing this innovation
Key Innovators
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA CORP
PHILADELPHIA, US
Higher Education Institute / Research Centre
INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS
ATHINA, GR
Higher Education Institute / Research Centre
UNIVERSITAT DES SAARLANDES
SAARBRUCKEN, DE
Higher Education Institute / Research Centre
The EU-funded Research Project
This innovation was developed under the FP7 project CHIC with an end date of 31/03/2017
  • Read more about this project on CORDIS
Description of Project CHIC
Developing robust, reproducible, interoperable and collaborative hyper-models of diseases and normal physiology is a sine qua non necessity if rational, coherent and comprehensive exploitation of the invaluable information hidden within human multiscale biological data is envisaged. Responding to this imperative in the context of both the broad Virtual Physiological Human (VPH) initiative and the paradigmatic cancer domain, CHIC proposes the development of a suite of tools, services and secure infrastructure that will support accessibility and reusability of VPH mathematical and computational hypermodels. These will include a hypermodelling infrastructure consisting primarily of a hypermodelling editor and a hypermodelling execution environment, an infrastructure for semantic metadata management, a hypermodel repository, a hypermodel-driven clinical data repository, a distributed metadata repository and an in silico trial repository for the storage of executed simulation scenarios. Multiscale models and data will be semantically annotated using the ontological and annotating tools to be developed. An image processing and visualization toolkit, and cloud and virtualization services will also be developed. The CHIC tools, services, infrastructure and repositories will provide the community with a collaborative interface for exchanging knowledge and sharing work in an effective and standardized way. A number of open source features and tools will enhance usability and accessibility. In order to ensure clinical relevance and foster clinical acceptance of hypermodelling in the future, the whole endeavour will be driven by the clinical partners of the consortium. Cancer hypermodels to be collaboratively developed by the consortium cancer modellers will provide the framework and the testbed for the development of the CHIC technologies. Clinical adaptation and partial clinical validation of hypermodels and hypermodel oncosimulators will be undertaken.

Innnovation Radar's analysis of this innovation is based on data collected on 24/05/2017.