Innovation

A set of clinically driven multiscale hypermodels simulating tumor growth and response to treatment

Market Maturity

These are innovations that are progressing on technology development process (e.g. pilots, prototypes, demonstration).More about market maturity categories

Innovation topic

Health & Care

Date of analysis

Innovation Radar's analysis of this innovation is based on data collected on 24/05/2017

Go to market needs

Needs that, if addressed, can increase the chances this innovation gets to (or closer to) the market incude:

  • Prepare for Market entry
  • Secure capital
  • Scale-up market opportunities
  • Project

    This innovation was developed under the FP7 project CHIC. Details of this project are provided below:

    Project acronym: CHIC

    Project Title: Computational Horizons In Cancer (CHIC): Developing Meta- and Hyper-Multiscale Models and Repositories for In Silico Oncology

    Project description: Developing robust, reproducible, interoperable and collaborative hyper-models of diseases and normal physiology is a sine qua non necessity if rational, coherent and comprehensive exploitation of the invaluable information hidden within human multiscale biological data is envisaged. Responding to this imperative in the context of both the broad Virtual Physiological Human (VPH) initiative and the paradigmatic cancer domain, CHIC proposes the development of a suite of tools, services and secure infrastructure that will support accessibility and reusability of VPH mathematical and computational hypermodels. These will include a hypermodelling infrastructure consisting primarily of a hypermodelling editor and a hypermodelling execution environment, an infrastructure for semantic metadata management, a hypermodel repository, a hypermodel-driven clinical data repository, a distributed metadata repository and an in silico trial repository for the storage of executed simulation scenarios. Multiscale models and data will be semantically annotated using the ontological and annotating tools to be developed. An image processing and visualization toolkit, and cloud and virtualization services will also be developed. The CHIC tools, services, infrastructure and repositories will provide the community with a collaborative interface for exchanging knowledge and sharing work in an effective and standardized way. A number of open source features and tools will enhance usability and accessibility. In order to ensure clinical relevance and foster clinical acceptance of hypermodelling in the future, the whole endeavour will be driven by the clinical partners of the consortium. Cancer hypermodels to be collaboratively developed by the consortium cancer modellers will provide the framework and the testbed for the development of the CHIC technologies. Clinical adaptation and partial clinical validation of hypermodels and hypermodel oncosimulators will be undertaken.

    Project end date: 31/03/2017

    More info:

    • Read more about this project on CORDIS (find names of contact persons and their phone numbers on the CORDIS page)

    Key Innovator(s)

    THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA CORP

    PHILADELPHIA, US

    Higher Education Instutite / Research Centre

    INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS

    ATHINA, EL

    Higher Education Instutite / Research Centre

    UNIVERSITAET DES SAARLANDES

    SAARBRUCKEN, DE

    Higher Education Instutite / Research Centre